SARS-CoV-2 Small Molecule Inhibitors
Viral Entry
| Product | Cat. No. | Target | Antiviral Activity |
|---|---|---|---|
| Amastatin . hydrochloride | 10-016 | Viral entry ANPEP (Aminopeptidase N) | Viral Replication |
| Camostat . mesylate | 10-017 | Viral entry TMPRSS2 | Viral Replication |
| Nafamostat . mesylate | 10-031 | Viral entry TMPRSS2 | Viral Replication |
| Umifenovir . HCl [Arbidol] | 10-048 | Viral entry Fusion into host cells | Viral Replication |
Lysosome/Endosome
| Product | Cat. No. | Target | Antiviral Activity |
|---|---|---|---|
| Chloroquine . diphosphate | 10-018 | Lysosome function Zinc ionophore | Viral Replication |
| Hydroxychloroquine . sulfate | 10-019 | Lysosome function Zinc ionophore | Viral Replication |
| Niclosamide | 10-033 | Endosome acidification | Viral Replication |
| Niclosamide . ethanolamine | 10-034 | Endosome acidification | Viral Replication |
Viral Protease
| Product | Cat. No. | Target | Antiviral Activity |
|---|---|---|---|
| Darunavir | 10-021 | Papain-like viral protease (PLVP) | Viral Maturation/Replication |
| Darunavir . ethanolate | 10-022 | Papain-like viral protease (PLVP) | Viral Maturation/Replication |
| Famotidine | 10-026 | SARS-CoV-2 papain-like protease (PLpro) | Viral Replication |
| Mycophenolic acid | 10-030 | SARS-CoV-2 papain-like protease (PLpro) | Viral Replication |
| Ebselen | 10-023 | Main Protease (Mpro)/3C-like Protease | Viral Transcription/Replication |
| Shikonin | 10-045 | Main Protease (Mpro)/3C-like Protease | Viral Transcription/Replication |
| Rosuvastatin . calcium salt | 10-041 | Main Protease Mpro | Viral Replication |
| Saquinavir . mesylate | 10-044 | Main Protease Mpro | Viral Replication |
Viral RNA-dependent RNA polymerase (RdRps)
| Product | Cat. No. | Target | Antiviral Activity |
|---|---|---|---|
| Remdesivir | 10-037 | RNA-dependent RNA polymerases (RdRps) | Viral Transcription/Replication |
| Remdesivir Metabolite (GS-441524) | 10-038 | RNA-dependent RNA polymerases (RdRps) | Viral Transcription/Replication |
| EIDD-2801 | 10-024 | RNA-dependent RNA polymerases (RdRps) | Viral Transcription/Replication |
| Favipiravir | 10-027 | RNA-dependent RNA polymerases (RdRps) | Viral Transcription/Replication |
| Elbasvir | 10-025 | RdRP, Papain-like Proteinase and Helicase | Viral Replication |
| Ribavirin | 10-039 | RNA-dependent RNA polymerases (RdRps) RNA capping activity Viral mutation rates Immunomodulation | Viral Transcription/Replication |
JAK Immunomodulation
| Product | Cat. No. | Target | Antiviral Activity |
|---|---|---|---|
| Ruxolitinib (free base) | 10-042 | JAK1/JAK2 Immunomodulation | Viral Replication |
| Ruxolitinib . phosphate salt | 10-043 | JAK1/JAK2 Immunomodulation | Viral Replication |
| Tofacitinib | 10-046 | JAK1/JAK2 Immunomodulation | Viral Replication |
| Tofacitinib . citrate | 10-047 | JAK1/JAK2 Immunomodulation | Viral Replication |
Other Chemicals
| Product | Cat. No. | Target | Antiviral Activity |
|---|---|---|---|
| Imatinib . mesylate | 10-028 | Virion fusion with endosomal membrane | Viral Replication |
| Nelfinavir . mesylate | 10-032 | Post-entry inhibitor | Viral Replication |
| Nitazoxanide | 10-035 | Viral hemagglutinin Viral IE2 | Viral Maturation/Transcription/Replication |
| Oseltamivir . phosphate | 10-036 | Viral neuraminidase Release of viral particles | Viral Replication |
| Lopinavir | 10-029 | Coronavirus endopeptidase C30 (CEP_C30) | Viral Maturation/Replication |
| Ritonavir | 10-040 | Coronavirus endopeptidase C30 (CEP_C30) | Viral Maturation/Replication |