TRIM45 Antibody Cat. No.: 25-851

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psi-iconSpecifications
HOST SPECIES:Rabbit
SPECIES REACTIVITY: Human, Mouse, Rat
IMMUNOGEN: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TRIM45.
TESTED APPLICATIONS: ELISA, WB
APPLICATIONS: TRIM45 antibody can be used for detection of TRIM45 by ELISA at 1:62500. TRIM45 antibody can be used for detection of TRIM45 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
POSITIVE CONTROL:1) Cat. No. 1201 - HeLa Cell Lysate
PREDICTED MOLECULAR WEIGHT: 64 kDa

psi-iconProperties
PURIFICATION:Antibody is purified by peptide affinity chromatography method.
CLONALITY:Polyclonal
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
CONCENTRATION:batch dependent
STORAGE CONDITIONS:For short periods of storage (days) store at 4˚C. For longer periods of storage, store TRIM45 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

psi-iconAdditional Info
OFFICIAL SYMBOL:TRIM45
ALTERNATE NAMES:TRIM45, FLJ13181, RNF99
ACCESSION NO.:NP_079464
PROTEIN GI NO.:224548921
GENE ID:80263
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:TRIM45 is a member of the tripartite motif family. It may function as a transcriptional repressor of the mitogen-activated protein kinase pathway. Alternatively spliced transcript variants have been described. TRIM45 belongs to a family of tripartite motif (TRIM) proteins that play important roles in a variety of cellular functions, including cell proliferation, differentiation, development, oncogenesis, and apoptosis (Wang et al., 2004 [PubMed 15351693]).
REFERENCES:1) Gregory, S.G., (2006) Nature 441 (7091), 315-321.

ANTIBODIES FOR RESEARCH USE ONLY.

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