TRADD Antibody Cat. No.: 13-070

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psi-iconSpecifications
HOST SPECIES:Rabbit
SPECIES REACTIVITY: Human
IMMUNOGEN: A synthetic peptide of human TRADD
TESTED APPLICATIONS: Flow, IF, IHC, WB
APPLICATIONS: WB: ,1:500 - 1:1000

IHC: ,1:50 - 1:100

IF: ,1:20 - 1:50

Flow: ,1:20 - 1:50
POSITIVE CONTROL:1) HeLa
PREDICTED MOLECULAR WEIGHT: Observed: 31kDa

psi-iconProperties
PURIFICATION:Affinity purification
CLONALITY:Polyclonal
ISOTYPE:IgG
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:PBS with 0.02% sodium azide, pH7.3.
STORAGE CONDITIONS:Store at 4˚C. Avoid freeze / thaw cycles.

psi-iconAdditional Info
OFFICIAL SYMBOL:TRADD
ALTERNATE NAMES:Tumor necrosis factor receptor type 1-associated DEATH domain protein, TNFR1-associated DEATH domain protein, TNFRSF1A-associated via death domain, TRADD
GENE ID:8717
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway.

ANTIBODIES FOR RESEARCH USE ONLY.

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