Specifications
| HOST SPECIES: | Rabbit |
| SPECIES REACTIVITY: |
Virus |
| IMMUNOGEN: |
Synthetic Peptide |
| TESTED APPLICATIONS: |
IHC, WB |
| APPLICATIONS: |
WB: 1:500 - 1:2000, IHC: 1:50 - 1:200 |
Properties
| PURIFICATION: | Affinity purification |
| CLONALITY: | Monoclonal |
| ISOTYPE: | IgG |
| CONJUGATE: | Unconjugated |
| PHYSICAL STATE: | Liquid |
| BUFFER: | PBS with 0.02% sodium azide, 50% glycerol, pH 7.3 |
| STORAGE CONDITIONS: | Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze-thaw cycles. |
Additional Info
| OFFICIAL SYMBOL: | TMPRSS2 |
| ALTERNATE NAMES: | PP9284, PRSS10, transmembrane serine protease 2 |
| ACCESSION NO.: | O15393 |
| GENE ID: | 7113 |
| USER NOTE: | Optimal dilutions for each application to be determined by the researcher. |
Background and References
| BACKGROUND: | This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008] |
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