TACI Antibody (biotin) Cat. No.: XP-5278Bt

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psi-iconSpecifications
HOST SPECIES:Goat
SPECIES REACTIVITY: Human
IMMUNOGEN: Produced from sera of goats pre-immunized with highly pure (>98%) recombinant hTACI (human TACI).
TESTED APPLICATIONS: ELISA, WB
APPLICATIONS: ELISA:

Sandwich:
To detect hTACI by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25 - 1.0 μg/mL of this antibody is required. This biotinylated polyclonal antibody, in conjunction with our Polyclonal Anti-Human TACI (XP-5278) as a capture antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hTACI.

Western Blot:

To detect hTACI by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for recombinant hTACI is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.
POSITIVE CONTROL:1) Cat. No. 1204 - K562 Cell Lysate
 2) Cat. No. 1215 - U937 Cell Lysate

psi-iconProperties
PURIFICATION:Anti-hTACI specific antibody was purified by affinity chromatography and then biotinylated.
CLONALITY:Polyclonal
CONJUGATE:Biotin
PHYSICAL STATE:Lyophilized
STORAGE CONDITIONS:TACI antibody is stable for at least 2 years from date of receipt at -20˚C. The reconstituted antibody is stable for at least two weeks at 2-8˚C. Frozen aliquots are stable for at least 6 months when stored at -20˚C. Avoid repeated freeze-thaw cycles.

psi-iconAdditional Info
OFFICIAL SYMBOL:TNFRSF13B
ALTERNATE NAMES:CVID, RYZN, TACI, CD267, CVID2, TNFRSF14B
ACCESSION NO.:Q4ACX1
PROTEIN GI NO.:121943629
GENE ID:23495
USER NOTE:Centrifuge vial prior to opening.
psi-iconBackground and References
BACKGROUND:TACI is a lymphocyte specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein binds to both APRIL and BAFF and induces activation of the transcription factors NFAT (nuclear-factor of activated T cells), AP1, and NF kappa B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith Magenis syndrome region on chromosome 17.

ANTIBODIES FOR RESEARCH USE ONLY.

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