Somatic Cytochrome C Antibody [7H8.2C12] Cat. No.: 49-765

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psi-iconSpecifications
HOST SPECIES:Mouse
SPECIES REACTIVITY: Drosophila, Hamster, Horse, Human, Mouse, Rat
IMMUNOGEN: Somatic Cytochrome C monoclonal antibody was raised against amino acids 1 - 80 81-104 and 66-104 of Somatic Cytochrome C. (Pigeon)
TESTED APPLICATIONS: ICC, IHC, WB
APPLICATIONS: Somatic Cytochrome C antibody can be used in ELISA, immunohistochemistry starting at 5 μg/mL, immunocytochemistry, immunofluorescence, and immunoprecipitation.
SPECIFICITY: An approx. 15 kD band is observed. This recognizes total cytochrome C which includes both apocytochrome (i. e. cytochrome in the cytosol without heme attached) and holocytochrome (i. e cytochrome in the mitochondria with heme attached).

psi-iconProperties
PURIFICATION:Protein G Column
CLONALITY:Monoclonal
ISOTYPE:IgG2b
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:PBS, 0.05% BSA, 0.05% sodium azide.
CONCENTRATION:0.5 mg/ml
STORAGE CONDITIONS:Store Somatic Cytochrome C antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles.

psi-iconAdditional Info
OFFICIAL SYMBOL:CYCS
ALTERNATE NAMES:CYCS, CYC, HCS, THC4, Cytochrome c, Cytochrome c, somatic
ACCESSION NO.:P99999
PROTEIN GI NO.:42560196
GENE ID:54205
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:In addition to its well-known role in electron transport, cytochrome c (CYT) has been identified as a mediator of apoptosis or programmed cell death. Cytochrome c translocates from mitochondria into the cytoplasm in the early phases of apoptosis and plays a role in initiation of the apoptotic proteolytic cascade by activating caspase-3. Cytochrome c has been shown to bind Apaf-1. Apaf-1 has also been shown to activate capase-3.

ANTIBODIES FOR RESEARCH USE ONLY.

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