Single Domain Antibodies

Single domain antibodies (sdAbs) are recombinant single domain monoclonal antibodies of the form VHH (VHH) derived from naturally occurring camelid (e.g. Llama, Alpaca) and shark heavy chain antibodies. Since sdAbs can be raised against unique epitope targets inaccessible by conventional antibodies, they offer the ability for precision structural analysis through enhanced molecular and tissue penetration with high affinity and specificity.

ProSci is pleased to offer the following sdAb products to introduce a new capability to your research regimen in the areas of Immuno-Oncology and Immune Checkpoints in addition to SARS-CoV-2 Spike. ProSci recombinant monoclonal sdAbs are supplied as a His-tagged purified protein (Nickel column chromatography) containing a Myc-tag for detection.

Contact ProSci to discuss your sdAb target and detection needs.


Risk Free Immuno-Oncology (Immune Checkpoints) sdAbs

ProductCloneCat. No.ApplicationClonalitySpecies
PD-L1 sdAb F6A9 SD8639 Flow, ICC Monoclonal Llama
PD-L1 sdAb F2G2 SD8641 ELISA, ICC, IF Monoclonal Llama
PD-1 sdAb F1-2A8 SD8643 ELISA, Flow Monoclonal Llama
PD-1 sdAb F42D7 SD8645 ELISA, Flow Monoclonal Llama
PD-1 sdAb F3-4C9 SD8647 ELISA, Flow Monoclonal Llama
PD-1 sdAb F2-5F4 SD8649 ELISA, Flow Monoclonal Llama
PD-1 Detection Set Containing 4 clones SD8600 Monoclonal Llama
TIGIT sdAb 2B5 SD8824 ELISA, Flow, ICC, IF, IHC-P Monoclonal Llama
TIGIT sdAb 2F7 SD8827 ELISA, Flow, ICC, IF, IHC-P Monoclonal Llama
TIGIT sdAb 2C6 SD8828 ELISA, Flow, ICC, IF, IHC-P Monoclonal Llama
TIGIT sdAb 2C7 SD8829 ELISA, Flow, ICC, IF, IHC-P Monoclonal Llama
TIGIT sdAb 2D7 SD8830 ELISA, Flow, ICC, IF, IHC-P Monoclonal Llama
TIGIT Detection Set Containing 5 clones SD8800 Monoclonal Llama
LAG3 sdAb 2A11 SD8837 ELISA, Flow, IF, IHC-P Monoclonal Llama
LAG3 sdAb 1A6 SD8839 ELISA, Flow, IF, IHC-P Monoclonal Llama
LAG3 sdAb 2B11 SD8841 ELISA, Flow, IF, IHC-P Monoclonal Llama
LAG3 sdAb 1C6 SD8842 ELISA, Flow, IF, IHC-P Monoclonal Llama
LAG3 sdAb 1A8 SD8843 ELISA, Flow, IF, IHC-P Monoclonal Llama
LAG3 Detection Set Containing 5 clones SD8700 Monoclonal Llama


SARS-Coronavirus-2 sdAbs

ProductCloneCat. No.ApplicationClonalitySpecies
SARS-CoV-2 (COVID-19) S1 RBD sdAb [T4P3-B5] SD9431 ELISA Monoclonal Llama
SARS-CoV-2 (COVID-19) S1 RBD sdAb [T4P3-B7] SD9433 ELISA Monoclonal Llama
SARS-CoV-2 (COVID-19) S1 RBD sdAb [RBD-2B9] SD9437 ELISA Monoclonal Llama
SARS-CoV-2 (COVID-19) S1 RBD sdAb [TSP4-A12] SD9439 ELISA Monoclonal Llama
SARS-CoV-2 (COVID-19) S1 RBD sdAb [T5P7-G10] SD9441 ELISA Monoclonal Llama
SARS-CoV-2 (COVID-19) S1 RBD sdAb [T4P5-H12] SD9507 ELISA Monoclonal Llama
SARS-CoV-2 (COVID-19) S1 RBD sdAb [T3P1-C8] SD9511 ELISA Monoclonal Llama


ProSci is committed to furthering global research efforts to understand this novel virus and the disease it causes by offering a broad catalog of SARS-CoV-2 antibodies, recombinant proteins, and related research reagents. By offering reagents to viral accessory proteins, ProSci supports research into unique approaches in diagnostics (e.g. measuring patient serum antibody levels of ORF3b and ORF8) and therapeutics (e.g. inhibiting some of the accessory proteins can aid in overcoming immune evasion and suppression). Contact us to see how we can help.