| SPECIES: | SARS Spike protein |
| SOURCE SPECIES: | HEK293 cells |
| SEQUENCE: | Arg306-Phe527 |
| FUSION TAG: | His-Avi Tag |
| TESTED APPLICATIONS: | ELISA, WB |
| APPLICATIONS: | SDS-PAGE |
Specifications| PURITY: | > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC |
| PREDICTED MOLECULAR WEIGHT: | Predicted: 27.9kD Observed: 36-46kD due to glycosylation |
| PHYSICAL STATE: | Lyophilized |
| BUFFER: | 20mM PB (pH 7.4). 5 % trehalose is added as protectant before lyophilization. |
| STORAGE CONDITIONS: | Store in working aliquots at -20˚C. Avoid freeze/thaw cycles. |
| ALTERNATE NAMES: | S protein RBD, Spike glycoprotein Receptor-binding domain, S glycoprotein RBD, Spike protein RBD |
| ACCESSION NO.: | P59594 |
| BACKGROUND: | The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensinconverting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. |
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