SARS-CoV-2 Spike RBD Antibody, monoclonal, Chimeric Cat. No.: 11-582

Availability: In stock

$0.00

 Price Options

$0.00
psi-iconSpecifications
SPECIES REACTIVITY: Mouse
IMMUNOGEN: Anti-SARS-CoV-2 Spike RBD Antibody, Human IgM is a chimeric monoclonal antibody combining the constant domains of the human IgM molecule with mouse variable regions.
TESTED APPLICATIONS: ELISA, WB
SPECIFICITY: This product can recognize SARS-CoV-2 and SARS-CoV Spike Protein RBD domainn. No cross-reactivity is detected with Spike Protein RBD domain of other coronaviruses, including MERS-CoV, HCoV-229E, HCoV-NL63, HCoV-OC43 and HCoV-HKU1.

psi-iconProperties
PURIFICATION:>85% as determined by SDS-PAGE.
CLONALITY:Monoclonal
ISOTYPE:Human IgM | Kappa
CONJUGATE:Unconjugated
PHYSICAL STATE:Lyophilized
BUFFER:Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 . Normally trehalose is added as protectant before lyophilization.
CONCENTRATION:batch dependent
STORAGE CONDITIONS:For long term storage, the product should be stored at lyophilized state at -20˚C or lower..Please avoid repeated freeze-thaw cycles.This product is stable after storage at:.-20 to -70˚C for 12 months in lyophilized state from date of receipt;.-70˚C for 3 months under sterile conditions after reconstitution.

psi-iconAdditional Info
OFFICIAL SYMBOL:S
ALTERNATE NAMES:spike glycoprotein
GENE ID:43740568
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

ANTIBODIES FOR RESEARCH USE ONLY.

For additional information, visit ProSci's Terms & Conditions Page.