SARS-COV-2 Nucleocapsid Protein Antibody (biotin) Cat. No.: 24-043

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psi-iconSpecifications
HOST SPECIES:Rabbit
SPECIES REACTIVITY: Virus
IMMUNOGEN: Hek293 derived SARS-COV-2 Nucleocapsid Ser2-Ala419 Accession #YP_009724397.2
TESTED APPLICATIONS: ELISA
APPLICATIONS: SARS-COV-2 Nucleocapsid Sandwich Elisa:

ELISA Capture: Recommended Concentration:1-4ug/mL, Sample: SARS-CoV-2 Nucleocapsid Protein Antibody´╝łCAP)

ELISA Detection: Recommended Concentration:0.05-0.2ug/mL, Sample: Biotinylated SARS-CoV-2 Nucleocapsid Protein Antibody

Standard:Recommended Concentration: 1.56-100pg/mL, Sample: Recombinant SARS-COV-2 Nucleocapsid Protein with His tag

SPECIFICITY: SARS-COV-2

psi-iconProperties
PURIFICATION:Affinity purification

< 1.0 EU/ug of the protein by LAL method.
CLONALITY:Polyclonal
ISOTYPE:Rabbit IgG
CONJUGATE:Biotin
PHYSICAL STATE:Liquid
BUFFER:Supplied as a 0.2um filtered solution in PBS, pH 7.4 containing SARS-CoV-2 (2019-nCoV) Nucleocapsid Antibody at a concentration of 1mg/mL.
CONCENTRATION:1 mg/ml
STORAGE CONDITIONS:This antibody can be stored at 2˚C - 8˚C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20˚C to -80˚C. Preservative-Free.Avoid repeated freeze-thaw cycles.

psi-iconAdditional Info
OFFICIAL SYMBOL:N
ALTERNATE NAMES:SARS-CoV-2 Nucleocapsid Protein, SARS-CoV-2 NP, nucleocapsid protein [Severe acute respiratory syndrome coronavirus 2], novel coronavirus N Protein, novel coronavirus Nucleocapsid Protein, 2019-nCoV Nucleoprotein, 2019-nCoV N, 2019nCoV N, 2019-nCoV N Protein, 2019 peak N Protein, 2019-nCoV nucleocapsid protein.
ACCESSION NO.:YP_009724397.2
GENE ID:1489678
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.

ANTIBODIES FOR RESEARCH USE ONLY.

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