SARS-CoV-2 Nucleocapsid Control Antibody [4A1W0] Cat. No.: 11-087

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psi-iconSpecifications
SPECIES REACTIVITY: Virus
IMMUNOGEN: HEK293 derived SARS-COV-2 Nucleocapsid, amino acids Ser2-Ala419
TESTED APPLICATIONS: ELISA
SPECIFICITY: SARS-CoV-2

psi-iconProperties
PURIFICATION:Affinity Purified, Endotoxin Level: < 1.0 EU/ug of the protein by LAL method.
CLONALITY:Monoclonal
ISOTYPE:Human IgG
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:Supplied as a 0.2um filtered solution in PBS, pH 7.4.
CONCENTRATION:1mg/ml
STORAGE CONDITIONS:This antibody can be stored at 2˚C to -8˚C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20˚C to -80˚C. Preservative-Free. Avoid repeated freeze-thaw cycles.

psi-iconAdditional Info
OFFICIAL SYMBOL:N
ALTERNATE NAMES:SARS-CoV-2 Nucleocapsid Protein, SARS-CoV-2 NP, nucleocapsid protein [Severe acute respiratory syndrome coronavirus 2], novel coronavirus N Protein, novel coronavirus Nucleocapsid Protein, 2019-nCoV Nucleoprotein, 2019-nCoV N, 2019nCoV N, 2019-nCoV N Protein, 2019 peak N Protein, 2019-nCoV nucleocapsid protein.
ACCESSION NO.:#YP_009724397.2
PROTEIN GI NO.:1798174255
GENE ID:43740575
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.

ANTIBODIES FOR RESEARCH USE ONLY.

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