This recombinant protein can be used for WB, ELISA. For research use only.
BIOLOGICAL ACTIVITY:
Measured by its binding ability in a functional ELISA.Immobilized Recombinant Human ACE2 at 2 g/mL (100L/well ) can bind Recombinant nCoV-S1, The EC50 of nCoV-S1 is 0.25-0.45 μg/mL
Properties
PURITY:
> 90% as determined by SDS-PAGE; > 95% by HPLC.
PREDICTED MOLECULAR WEIGHT:
75.8 kDa
PHYSICAL STATE:
Lyophilized
BUFFER:
PBS, pH 7.4
STORAGE CONDITIONS:
Store the lyophilized protein at -20˚C to -20˚C for long term. After reconstitution, the protein solution is stable at -20˚C for 3 months, at 2-8˚C for up to 1 week
Additional Info
ALTERNATE NAMES:
S1 protein, Spike glycoprotein subunit 1, S glycoprotein subunit 1, Spike protein S1, Novel coronavirus S1 protein
ACCESSION NO.:
YP_009724390.1
OFFICIAL SYMBOL:
S
GENE ID:
43740568
Background and References
BACKGROUND:
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses as well as protective immunity.