SARS-CoV-2 (COVID-19) S1+S2 ECD (S-ECD) Recombinant Protein Cat. No.: 10-121

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psi-iconSpecifications
SPECIES:SARS-CoV-2 (COVID-19) Spike Protein
SOURCE SPECIES:HEK293 cells
SEQUENCE:Cys15-Gln1208 with mutation in the cleavage site (683 G)
FUSION TAG:His tag at C-terminus
TESTED APPLICATIONS:ELISA, WB
APPLICATIONS:This recombinant protein can be used for WB. For research use only.
BIOLOGICAL ACTIVITY: Measured by its binding ability in a functional ELISA. Immobilized Recombinant SARS-COV-2 Spike S1+S2 ECD at 2μg/mL (100 μL/well) can bind Recombinant Human ACE2 with a linear range of 0.15-3.03 ng/mL
psi-iconProperties
PURITY:> 97% as determined by SDS-PAGE.
PREDICTED MOLECULAR WEIGHT:132.29a
PHYSICAL STATE:Liquid
BUFFER:PBS, pH 7.4
STORAGE CONDITIONS:This product is stable at ≤ ‑70˚C for up to 6 months from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles.
psi-iconAdditional Info
ALTERNATE NAMES:2019-nCoV spike protein, 2019-nCoV S glycoprotein, COVID-19 S protein, Spike glycoprotein, SARS-CoV-2 Spike
ACCESSION NO.:QHD43416.1)
GENE ID:43740568
psi-iconBackground and References
BACKGROUND:The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses as well as protective immunity.

FOR RESEARCH USE ONLY.

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