| SPECIES: | SARS-CoV-2 (COVID-19, 2019-nCoV) Spike Protein |
| SOURCE SPECIES: | HEK293 cells |
| SEQUENCE: | Val11-Gln1208 |
| FUSION TAG: | His tag at C-terminus |
| TESTED APPLICATIONS: | ELISA, WB |
| APPLICATIONS: | This recombinant protein can be used for WB. For research use only. |
| BIOLOGICAL ACTIVITY: | Measured by its binding ability in a functional ELISA. Immobilized Recombinant 2019-nCoV Spike S1+S2 ECD-His at 2μg/mL (100 μL/well) can bind Recombinant Human ACE2 with a linear range of 1.5-115.4 ng/mL. |
Specifications| PURITY: | > 97% as determined by SDS-PAGE. |
| PREDICTED MOLECULAR WEIGHT: | 133.8 kDa |
| PHYSICAL STATE: | Liquid |
| BUFFER: | PBS, pH 7.4 |
| STORAGE CONDITIONS: | This product is stable at ≤ ‑70˚C for up to 6 months from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles. |
| ALTERNATE NAMES: | 2019-nCoV spike protein, 2019-nCoV S glycoprotein, COVID-19 S protein, Spike glycoprotein |
| ACCESSION NO.: | YP_009724390.1 |
| OFFICIAL SYMBOL: | S |
| GENE ID: | 43740568 |
| BACKGROUND: | The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses as well as protective immunity. |
FOR RESEARCH USE ONLY.
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