SARS-CoV-2 (COVID-19) NSP8 Recombinant Protein Cat. No.: 97-097

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psi-iconSpecifications
SPECIES:SARS-CoV-2
SOURCE SPECIES:E. coli
SEQUENCE:Ala 1 - Gln 198
FUSION TAG:His Tag at N-terminus
TESTED APPLICATIONS:WB
APPLICATIONS:This recombinant protein can be used for WB. For research use only.
psi-iconProperties
PURITY:>95% as determined by SDS-PAGE.
PREDICTED MOLECULAR WEIGHT:22-25 kDa
PHYSICAL STATE:Liquid
BUFFER:20 mM Tris, 250 mM NaCl, pH8.5 with glycerol 
STORAGE CONDITIONS:Working aliquots should be stored at -70˚C or lower. Avoid repeated freeze-thaw cycles.
psi-iconAdditional Info
ALTERNATE NAMES:NSP8, nsp8, Non-structural protein 8, COVID-19
ACCESSION NO.:YP_009725304.1
psi-iconBackground and References
BACKGROUND:NSP8, forms a hexadecamer with nsp7 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers. To ultimately combat the emerging COVID-19 pandemic, it is desired to develop an effective and safe vaccine against this highly contagious disease caused by the SARS-CoV-2 coronavirus. By investigating the entire proteome of SARS-CoV-2, six proteins, including the S protein and five non-structural proteins (nsp3, 3CL-pro, and nsp8-10) were predicted to be adhesins, which are crucial to the viral adhering and host invasion. The S, nsp3, and nsp8 proteins were also predicted by Vaxign-ML to induce high protective antigenicity.
REFERENCES:1) te Velthuis AJ, et al. Nucleic Acids Res. 2012. 40(4):1737-47.
2) Edison Ong, et al. doi.org. 2020. 000141.

FOR RESEARCH USE ONLY.

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