SARS-CoV-2 (COVID-19) NSP10 Recombinant Protein Cat. No.: 10-408

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psi-iconSpecifications
SPECIES:SARS-CoV-2
SOURCE SPECIES:E. coli
SEQUENCE:Ala1-Gln139
FUSION TAG:N-His Tag
APPLICATIONS:Immunogen
BIOLOGICAL ACTIVITY: Testing in progress
psi-iconProperties
PURITY:>90% as determined by SDS-PAGE quantitative densitometry by Coomassie Blue Staining.
PREDICTED MOLECULAR WEIGHT:17.99kDa
PHYSICAL STATE:Lyophilized
BUFFER:Supplied as lyophilized from PBS, pH7.5
STORAGE CONDITIONS:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 ˚C for one week. Store at -20 to -80 ˚C for twelve months from the date of receipt.
psi-iconAdditional Info
ALTERNATE NAMES:nsp10,GFL
ACCESSION NO.:YP_009725306.1
psi-iconBackground and References
BACKGROUND:Nsp10 have shown that it is a 15-kDa protein of unknown function that has been shown to interact with itself, nsp1, and nsp7. It colocalizes with N to sites of viral replication and is essential for replication. It plays a pivotal role in viral transcription by stimulating both nsp14 3'-5' exoribonuclease and nsp16 2'-O-methyltransferase activities. Therefore plays an essential role in viral mRNAs cap methylation. Nsp10 is a critical regulator of coronavirus RNA synthesis and may play an important role in polyprotein processing.

FOR RESEARCH USE ONLY.

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