SARS-CoV-2 (COVID-19) Full-Length Kappa Variant (B.1.617.1, India) Spike Recombinant Protein Cat. No.: 21-823

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psi-iconSpecifications
SPECIES:SARS-CoV-2 (COVID-19, 2019-nCoV) Spike Protein
SOURCE SPECIES:HEK293 cells
SEQUENCE:Full-length sequence (aa 1 – 1273), G142D; E154K; L452R; E484Q
D614G; P681R; Q1071H
furin cleavage site “RRAR” mutated to “GSAG”; K986P; V987P
C-terminal Rho1D4 tag fused with spacer “GSSG” to protein sequence
FUSION TAG:C-terminal Rho1D4
TESTED APPLICATIONS:ELISA
APPLICATIONS:This recombinant protein can be used for ELISA assays, Ligand binding assays (e.g. SPR), Biochemical and biophysical analyses. For research use only.
BIOLOGICAL ACTIVITY: not determined
psi-iconProperties
PURITY:>98% as determined by SDS-PAGE, see Fig. 1 A and B. PureCube Rho1D4 Agarose.
PREDICTED MOLECULAR WEIGHT:1286 amino acids (including Rho1D4 tag and linker); 142115.37 Da
PHYSICAL STATE:Liquid
BUFFER:20 mM Hepes pH 7.5; 150 mM NaCl, 0.001 % LMNG
CONCENTRATION:batch dependent
STORAGE CONDITIONS:–80˚C. Avoid freeze-thaw cycles
psi-iconAdditional Info
ALTERNATE NAMES:SARS-CoV-2 (COVID-19) Spike Recombinant Protein: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Surface Glycoprotein, Spike protein
OFFICIAL SYMBOL:S
GENE ID:43740568
psi-iconBackground and References
BACKGROUND:All viruses undergo fast mutations and adapt quickly to the countermeasures that the immune systems creates. SARS-CoV-2 of the COVID-19 pandemic is no exception to this. During the pandemic multiple mutant strains arose. To help the sciencific community to combat these mutants ProSci offers the SPIKE protein of the mutants in full-length and active in their native trimeric form, stabilized with the LMNG detergent. This is the spike protein of the mutant strain B.1.429, also known as mutant strain CAL.20C or "California mutant".

FOR RESEARCH USE ONLY.

For additional information, visit ProSci's Terms & Conditions Page.