SARS-CoV-2 (COVID-19) Envelope Recombinant Protein Cat. No.: 92-730

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psi-iconSpecifications
SPECIES:SARS-CoV-2 (COVID-19, 2019-nCoV) Envelope Protein
SOURCE SPECIES:E. coli
SEQUENCE:Met1-Val75
FUSION TAG:N-BBP-6His tag
APPLICATIONS:This recombinant protein can be used for biological assays. For research use only.
psi-iconProperties
PURITY:Greater than 95% as determined by reducing SDS-PAGE.
PREDICTED MOLECULAR WEIGHT:27.5kDa, 22-25kDa
PHYSICAL STATE:Liquid
BUFFER:Supplied as a 0.2 uM filtered solution of 20mM Tris–HCl, 200mM NaCl, pH 8.0
STORAGE CONDITIONS:Reconstituted protein solution should be store below -20˚C.
psi-iconAdditional Info
ALTERNATE NAMES:2019-nCoV E protein; 2019-nCoV sM protein
ACCESSION NO.:QHD43418.1
OFFICIAL SYMBOL:E
GENE ID:43740570
psi-iconBackground and References
BACKGROUND:These proteins are involved in viral morphogenesis and tropism, and their absence leads in some cases to aberrant virions, or to viral attenuation. In common to other viroporins, coronavirus envelope proteins increase membrane permeability to ions, plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis. Activates the host NLRP3 inflammasome, leading to IL-1beta overproduction.

FOR RESEARCH USE ONLY.

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