The Recombinant SARS-CoV Nucleocapsid Protein is manufactured with N-terminal fusion His Tag. The Recombinant SARS-CoV Nucleocapsid His-Tagged Fusion Protein is 47.8kDa containing 437 amino acid residues of the SARS-CoV Nucleocapsid protein and 16 additional amino acid residues – His Tag (underlined).
FUSION TAG:
His Tag
BIOLOGICAL ACTIVITY:
N/A
Properties
PURITY:
>95% as determined by SDS-PAGE.
PHYSICAL STATE:
Liquid
BUFFER:
Sterile filtered (0,4µm) and lyophilized from 0.5 mg/ml in 0.05M Acetate buffer pH4.
STORAGE CONDITIONS:
Store in working aliquots at -20˚C. Avoid freeze/thaw cycles.
Background and References
BACKGROUND:
SARS Coronavirus is an enveloped virus containing three outer structural proteins, namely the membrane (M), envelope (E), and spike (S) proteins. Spike (S)-glycoprotein of the virus interacts with a cellular receptor and mediates membrane fusion to allow viral entry into susceptible target cells. Accordingly, S-protein plays an important role in virus infection cycle and is the primary target of neutralizing antibodies.
Specifications
