The E.coli derived recombinant protein contains the Nucleocapsid protein 340-390 amino acids immunodominant regions fused to 6xHis tag at C-terminal.
FUSION TAG:
His Tag
BIOLOGICAL ACTIVITY:
N/A
Properties
PURITY:
>90% pure as determined SDS-PAGE. Purified by proprietary chromatographic technique.
PHYSICAL STATE:
Liquid
BUFFER:
SARS Nucleocapsid protein solution is supplied in PBS.
STORAGE CONDITIONS:
Store in working aliquots at -20˚C. Avoid freeze/thaw cycles.
Background and References
BACKGROUND:
SARS-Associated Coronavirus Nuclecapsid is an enveloped viral componentthat contains three external structural antigens, the mains are membrane (M), envelope (E), and spike (S) proteins. Spike (S)-glycoprotein of the virus interacts with a membrenal receptor and mediates membrane fusion to grant viral entry into the target cells. therefore, S-protein has a crucial part in virus infection cycle and is the main target of neutralizing antibodies.
Specifications
