Rhesus macaque CD155 / PVR Recombinant Protein Cat. No.: 11-429

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psi-iconSpecifications
SPECIES:Rhesus monkey
SOURCE SPECIES:HEK293 cells
SEQUENCE:Asp 28 - Asn 343
FUSION TAG:His Tag
TESTED APPLICATIONS:ELISA, WB
APPLICATIONS:This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 36.3 kDa. The protein migrates as 48-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
psi-iconProperties
PURITY:>90% as determined by SDS-PAGE.
PREDICTED MOLECULAR WEIGHT:36.3 kDa
PHYSICAL STATE:Lyophilized
BUFFER:PBS, pH7.4
STORAGE CONDITIONS:Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
psi-iconAdditional Info
ALTERNATE NAMES:PVR,FLJ25946,PVS,CD155,TAGE4,HVED,NECL5
ACCESSION NO.:NP_001036851.1
OFFICIAL SYMBOL:PVR
GENE ID:712851
psi-iconBackground and References
BACKGROUND:CD155 (cluster of differentiation 155) also known as the poliovirus receptor is a protein that is encoded by the PVR gene. CD155 is a Type I transmembrane glycoprotein in the immunoglobulin superfamily. Commonly known as Poliovirus Receptor (PVR) due to its involvement in the cellular poliovirus infection in primates, CD155's normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. The role of CD155 in the immune system is unclear, though it may be involved in intestinal humoral immune responses. Subsequent data has also suggested that CD155 may also be used to positively select MHC-independent T cells in the thymus.
REFERENCES:1) Zhang P., et al., 2008, Proc. Natl. Acad. Sci., 105 (47): 18284-18289.
2) Maier MK., et al., 2007, European Journal of Immunology, 37 (8): 2214-2225.
3) He Y., et al., 2000, Proc. Natl. Acad. Sci., 97 (1): 79-84.

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