SPECIES: | Rhesus monkey |
SOURCE SPECIES: | Mammalian cells |
SEQUENCE: | Gln18-Val739 |
FUSION TAG: | C-Fc tag |
APPLICATIONS: | This recombinant protein can be used for biological assays. For research use only. |
PURITY: | Greater than 95% as determined by reducing SDS-PAGE. Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test. |
PREDICTED MOLECULAR WEIGHT: | 110.6kDa |
PHYSICAL STATE: | Liquid |
BUFFER: | Supplied as a 0.2 um filtered solution of PBS, pH 7.4. |
STORAGE CONDITIONS: | Store below -20˚C, stable for 6 months after receipt. |
ALTERNATE NAMES: | Angiotensin-Converting Enzyme 2; ACE-Related Carboxypeptidase; Angiotensin-Converting Enzyme Homolog; ACEH; Metalloprotease MPROT15; ACE2 |
ACCESSION NO.: | ACI04564.1 |
OFFICIAL SYMBOL: | Ace2 |
GENE ID: | 712790 |
BACKGROUND: | Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function. |
FOR RESEARCH USE ONLY.
For additional information, visit ProSci's Terms & Conditions Page.