| HOST SPECIES: | Human |
| SPECIES REACTIVITY: | Virus |
| IMMUNOGEN: | Cultured in vitro under conditions free from animal derived components. |
| TESTED APPLICATIONS: | ELISA |
| APPLICATIONS: | Immunoreactivity: 80-120 % compared to the reference sample in an ELISA test. |
| SPECIFICITY: | Antibody recognizes 2019-nCoV Nucleocapsid Protein |
Specifications| PURIFICATION: | ≥95 % |
| CLONALITY: | Monoclonal |
| ISOTYPE: | Human IgG1 |
| CONJUGATE: | Unconjugated |
| PHYSICAL STATE: | Liquid |
| BUFFER: | PBS, pH 7.4 |
| CONCENTRATION: | 5.0 mg/ml (+/- 10 %) |
| STORAGE CONDITIONS: | 24 months from manufacturing at <-20 ˚C; 1 month, 2 to 8 ˚C under sterile conditions. |
| OFFICIAL SYMBOL: | N |
| ALTERNATE NAMES: | SARS-CoV-2 (COVID-19) Nucleocapsid Antibody: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Nucleocapsid protein, N protein, Nucleocapsid Phosphoprotein |
| ACCESSION NO.: | QHD43423 |
| PROTEIN GI NO.: | 1820552696 |
| GENE ID: | 43740575 |
| USER NOTE: | Optimal dilutions for each application to be determined by the researcher. |
| BACKGROUND: | Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. N protein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool. |
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