This recombinant protein can be used for WB, ELISA, MS.
BIOLOGICAL ACTIVITY:
N/A
Properties
PURITY:
95%
PREDICTED MOLECULAR WEIGHT:
44.7 kDa (Calculated)
PHYSICAL STATE:
Liquid
BUFFER:
10 mM Tris, pH 8.0, 0.1% Triton X-100, 0.002% NaN3
STORAGE CONDITIONS:
Store in working aliquots at -70˚C. Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 α subunits and 2 rings are composed of 7 β subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.
Specifications
