PSMC6 Recombinant Protein Cat. No.: XW-RP3212

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psi-iconSpecifications
SPECIES:Human
SOURCE SPECIES:E. coli
SEQUENCE:aa. 1-389
TESTED APPLICATIONS:ELISA, MS, WB
APPLICATIONS:This recombinant protein can be used for WB, ELISA, MS.
BIOLOGICAL ACTIVITY: N/A
psi-iconProperties
PURITY:95%
PREDICTED MOLECULAR WEIGHT:44.7 kDa (Calculated)
PHYSICAL STATE:Liquid
BUFFER:10 mM Tris, pH 8.0, 0.1% Triton X-100, 0.002% NaN3
STORAGE CONDITIONS:Store in working aliquots at -70˚C. Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
psi-iconAdditional Info
ALTERNATE NAMES:P44, p42, SUG2, CADP44, HEL-S-73, 26S protease regulatory subunit 10B, 26S proteasome AAA-ATPase subunit RPT4
ACCESSION NO.:NP_002797
PROTEIN GI NO.:24430160
OFFICIAL SYMBOL:PSMC6
GENE ID:5706
psi-iconBackground and References
BACKGROUND:The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 α subunits and 2 rings are composed of 7 β subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.

FOR RESEARCH USE ONLY.

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