Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: ZBTB1 antibody was raised against a 14 amino acid synthetic peptide near the center of human ZBTB1.
The immunogen is located within amino acids 260 - 310 of ZBTB1. - CONJUGATE: Unconjugated
- TESTED APPLICATIONS: ELISA, IHC-P, WB
- APPLICATION NOTE: ZBTB1 antibody can be used for detection of ZBTB1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested. - SPECIFICITY: At least two isoforms of ZBTB1 are known to exist. This ZBTB1 antibody will not cross-react with ZBTB2.
- POSITIVE CONTROL 1: Cat. No. 1211 - HepG2 Cell Lysate
Properties
- PURIFICATION: ZBTB1 Antibody is affinity chromatography purified via peptide column.
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: ZBTB1 Antibody is supplied in PBS containing 0.02% sodium azide.
- CONCENTRATION: 1 mg/mL
- STORAGE CONDITIONS: ZBTB1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: ZBTB1
- ADDITIONAL NAMES: ZBTB1 Antibody: ZNF909, KIAA0997, Zinc finger and BTB domain-containing protein 1
- Protein Accession Number: AAH50719
- PROTEIN GI NUMBER: 29792103
- NCBI GENE ID NUMBER: 22890
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- ZBTB1 Antibody: ZBTB1 is a zinc finger protein that also contains BTB (BR-C, ttk and bab) domain. While little is known about this protein or the related protein ZBTB2, its expression is known to be down-regulated in human bronchial epithelial cells in response to the presence of Vanadium. Recently, expression of variant ZBTB1 protein has been associated with increased age-related macular degeneration.
- 1: Strausberg RL, Feingold EA, Grouse LH, et al. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. USA2002; 99:16899-903.
- 2: Li Z, Stonehuerner J, Devlin RB, et al. Discrimination of Vanadium from Zinc using gene profiling in human bronchial epithelial cells. Envir. Health Perspect.2005; 113:1747-54.
- 3: Zhang H, Morrison MA, Dewan A, et al. The NEI/NCBI dbGAP database: genotypes and haplotypes that may specifically predispose to risk of neovascular age-related macular degeneration. BMC Med. Genet.2008; 9:51.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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