YLAT2 Antibody
CATALOG NUMBER: 61-876- Clonality: Polyclonal
- Tested Applications: Flow, WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This YLAT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 487-515 amino acids from the C-terminal region of human YLAT2.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: Flow, WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50 - PREDICTED MOLECULAR WEIGHT: 57 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: SLC7A6
- ADDITIONAL NAMES: Y+L amino acid transporter 2, Cationic amino acid transporter, y+ system, Solute carrier family 7 member 6, y(+)L-type amino acid transporter 2, Y+LAT2, y+LAT-2, SLC7A6 (HGNC:11064)
- Protein Accession Number: Q92536
- PROTEIN GI NUMBER: 190462822
- NCBI GENE ID NUMBER: 9057
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This protein involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. It requires co-expression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. It also acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. It plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. It involved in the transport of L-arginine in monocytes and reduces uptake of ornithine in retinal pigment epithelial (RPE) cells.
- 1: Sekine, Y., et al. J. Am. Soc. Nephrol. 20(7):1586-1596(2009)
- 2: Broer, S. Physiol. Rev. 88(1):249-286(2008)
- 3: Xu, D., et al. Mol. Cell Proteomics 4(8):1061-1071(2005)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
$65 Standard Overnight flat rate for as many products shipped within the United States.
$35 Dry Ice Shipment fee may be required on some items.
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