XRN2 Antibody
CATALOG NUMBER: 57-673- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- HOMOLOGY: Predicted species reactivity based on immunogen sequence: Chicken, Drosophila, Mouse
- IMMUNOGEN: This XRN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-76 amino acids from the N-terminal region of human XRN2.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 109 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: XRN2
- ADDITIONAL NAMES: 5'-3' exoribonuclease 2, 3113-, DHM1-like protein, DHP protein, XRN2
- Protein Accession Number: Q9H0D6
- PROTEIN GI NUMBER: 30173484
- NCBI GENE ID NUMBER: 22803
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene shares similarity with the mouse Dhm1 and theyeast dhp1 gene. The yeast gene is involved in homologousrecombination and RNA metabolism, such as RNA synthesis and RNAtrafficking. Complementation studies show that Dhm1 has a similarfunction in mouse as dhp1. The function of the human gene has notyet been determined. Transcript variants encoding differentisoforms have been noted for this gene; however, their full-lengthnature is not known.
- 1: Lu, Y., et al. Oncogene 29(7):1041-1049(2010)
- 2: Yang, X.C., et al. Mol. Cell. Biol. 29(1):31-42(2009)
- 3: Kaneko, S., et al. Genes Dev. 21(14):1779-1789(2007)
- 4: Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
$65 Standard Overnight flat rate for as many products shipped within the United States.
$35 Dry Ice Shipment fee may be required on some items.
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