WDR4 Antibody
CATALOG NUMBER: 59-281- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- HOMOLOGY: Predicted species reactivity based on immunogen sequence: Bovine, Mouse
- IMMUNOGEN: This WDR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 146-173 amino acids from the Central region of human WDR4.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 45 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: WDR4
- ADDITIONAL NAMES: tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 {ECO:0000255 | HAMAP-Rule:MF_03056}, WD repeat-containing protein 4 {ECO:0000255 | HAMAP-Rule:MF_03056}, WDR4 {ECO:0000255 | HAMAP-Rule:MF_03056}
- Protein Accession Number: P57081
- PROTEIN GI NUMBER: 20141943
- NCBI GENE ID NUMBER: 10785
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene encodes a member of the WD repeat proteinfamily. WD repeats are minimally conserved regions of approximately40 amino acids typically bracketed by gly-his and trp-asp (GH-WD),which may facilitate formation of heterotrimeric or multiproteincomplexes. Members of this family are involved in a variety ofcellular processes, including cell cycle progression, signaltransduction, apoptosis, and gene regulation. This gene is excludedas a candidate for a form of nonsyndromic deafness (DFNB10), but isstill a candidate for other disorders mapped to 21q22.3 as well asfor the development of Down syndrome phenotypes. Two transcriptvariants encoding the same protein have been found for this gene.
- 1: Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
- 2: Olsen, J.V., et al. Cell 127(3):635-648(2006)
- 3: Hu, Y.H., et al. BMC Genomics 7, 155 (2006) :
- 4: Cartlidge, R.A., et al. EMBO J. 24(9):1696-1705(2005)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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