Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- HOMOLOGY: Predicted species reactivity based on immunogen sequence: Bovine, Mouse
- IMMUNOGEN: This WASF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-190 amino acids from the Central region of human WASF2.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 54 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: WASF2
- ADDITIONAL NAMES: Wiskott-Aldrich syndrome protein family member 2, WASP family protein member 2, Protein WAVE-2, Verprolin homology domain-containing protein 2, WASF2, WAVE2
- Protein Accession Number: Q9Y6W5
- PROTEIN GI NUMBER: 59800456
- NCBI GENE ID NUMBER: 10163
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene encodes a member of the Wiskott-Aldrich syndromeprotein family. The gene product is a protein that forms amultiprotein complex that links receptor kinases and actin. Bindingto actin occurs through a C-terminal verprolin homology domain inall family members. The multiprotein complex serves to tranducesignals that involve changes in cell shape, motility or function.The published map location (PMID:10381382) has been changed basedon recent genomic sequence comparisons, which indicate that theexpressed gene is located on chromosome 1, and a pseudogene may belocated on chromosome X.
- 1: Takahashi, K., et al. Cell. Signal. 22(3):510-518(2010)
- 2: Lebensohn, A.M., et al. Mol. Cell 36(3):512-524(2009)
- 3: Cai, X., et al. Lung Cancer 65(3):299-305(2009)
- 4: Morimura, S., et al. Biochem. Biophys. Res. Commun. 382(3):614-619(2009)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
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