VANGL2 Antibody
CATALOG NUMBER: 60-897- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Mouse
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Mouse
- HOMOLOGY: Predicted species reactivity based on immunogen sequence: Rat
- IMMUNOGEN: This VANGL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human VANGL2.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 60 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: VANGL2
- ADDITIONAL NAMES: Vang-like protein 2, Loop-tail protein 1 homolog, Strabismus 1, Van Gogh-like protein 2, VANGL2, KIAA1215, STB1
- Protein Accession Number: Q9ULK5
- PROTEIN GI NUMBER: 38258849
- NCBI GENE ID NUMBER: 57216
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Planar cell polarity (PCP) is the term given to globalcell polarization, such as the alignment of mammalian body hairalong the anterior-posterior axis or the orientation of steriociliabundles in the inner ear. VANGL2 is a PCP protein that is involvedin the transmission of directional cues to align either individualcells within an epithelial sheet or multicellular clusters, whichpolarize as a group (Devenport and Fuchs, 2008 [PubMed18849982]).
- 1: Lei, Y.P., et al. N. Engl. J. Med. 362(23):2232-2235(2010)
- 2: Yates, L.L., et al. Hum. Mol. Genet. 19(11):2251-2267(2010)
- 3: Cantrell, V.A., et al. Cancer Lett. 287(1):54-61(2010)
- 4: Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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