UGT1A10 Antibody
CATALOG NUMBER: 16-648- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 50 uL
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human UGT1A10 (NP_061948.1).
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: WB: 1:500 - 1:2000
- POSITIVE CONTROL 1: LO2
- POSITIVE CONTROL 2: 293T
- POSITIVE CONTROL 3: A375
- PREDICTED MOLECULAR WEIGHT: Observed: 60kDa
Properties
- PURIFICATION: Affinity purification
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at -20°C. Avoid freeze / thaw cycles.
Additional Info
- NCBI OFFICIAL SYMBOL: UGT1A10
- ADDITIONAL NAMES: GNT1, UDPGT, UGT-1A, UGT-1J, UGT1, UGT1-01, UGT1-1UGT1.1, UGT1.1UGT1A, UGT1A1, UGT1J, hUG-BR1, UDP-glucuronosyltransferase 1-1Bilirubin-specific UDPGT isozyme 1, UDP glucuronosyltransferase 1 family, polypeptide A1UDP glycosyltransferase 1 family, polypeptide A1UDP-glucuronosyltransferase 1-1, UDP-glucuronosyltransferase 1-A, UDP-glucuronosyltransferase 1-J, UDP-glucuronosyltransferase 1A1, UDP-glucuronosyltransferase 1A1UDPGT 1-1, UDPGT 1-10
- NCBI GENE ID NUMBER: 54575
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has glucuronidase activity on mycophenolic acid, coumarins, and quinolines.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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