Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- HOMOLOGY: Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
- IMMUNOGEN: This UBTD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 180-212 amino acids from the C-terminal region of human UBTD1.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IHC-P, WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50 - PREDICTED MOLECULAR WEIGHT: 26 kDa
Properties
- PURIFICATION: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: UBTD1
- ADDITIONAL NAMES: Ubiquitin domain-containing protein 1, UBTD1
- Protein Accession Number: Q9HAC8
- PROTEIN GI NUMBER: 74752759
- NCBI GENE ID NUMBER: 80019
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- UBTD1 contains a ubiquitin domain, and has been demonstrated to bind to p53 in cells p53 is linked to the ubiquitination pathway through its transcriptional regulation of the four ubiquitin ligases, MDM2, COP1, Siah1b, and Pirh2. The role of UBTD1 has not been elucidated, however preliminary evidence indicates a potential role in p53 signaling.
- 1: Ota, T., et al., Nat. Genet. 36(1):40-45 (2004).
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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