TXNRD3 Antibody
CATALOG NUMBER: 60-626- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This TXNRD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 304-333 amino acids from the Central region of human TXNRD3.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 71 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: TXNRD3
- ADDITIONAL NAMES: Thioredoxin reductase 3, Thioredoxin and glutathione reductase, Thioredoxin reductase TR2, TXNRD3 {ECO:0000312 | EMBL:AAH500321}
- Protein Accession Number: Q86VQ6
- PROTEIN GI NUMBER: 510120859
- NCBI GENE ID NUMBER: 114112
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene encodes a member of the family of pyridinenucleotide oxidoreductases. This protein catalyzes the reduction ofthioredoxin, and is implicated in the defense against oxidativestress. It contains a selenocysteine (Sec) residue (which isessential for catalytic activity), encoded by a UGA codon, at thepenultimate C-terminal position. The 3' UTR of Sec-containing geneshave a common stem-loop structure, the sec insertion sequence(SECIS), which is necessary for the recognition of UGA as a Seccodon rather than as a stop signal. Alternatively splicedtranscript variants encoding different isoforms have been found forthis gene.
- 1: Gerashchenko, M.V., et al. J. Biol. Chem. 285(7):4595-4602(2010)
- 2: Starr, J.M., et al. Mech. Ageing Dev. 129(12):745-751(2008)
- 3: Harris, S.E., et al. BMC Genet. 8, 43 (2007) :
- 4: Kryukov, G.V., et al. Science 300(5624):1439-1443(2003)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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