- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human TSG101 (NP_006283.1).
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IHC, WB
- APPLICATION NOTE: WB: 1:500 - 1:2000
IHC: 1:50 - 1:100
- POSITIVE CONTROL 1: HeLa
- POSITIVE CONTROL 2: MCF7
- POSITIVE CONTROL 3: K-562
- POSITIVE CONTROL 4: Mouse spinal cord
- POSITIVE CONTROL 5: Rat heart
- POSITIVE CONTROL 6: Rat lung
- PREDICTED MOLECULAR WEIGHT: Observed: 44kDa
- PURIFICATION: Affinity purification
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at -20°C. Avoid freeze / thaw cycles.
- NCBI OFFICIAL SYMBOL: TSG101
- ADDITIONAL NAMES: TSG101, TSG10, VPS23
- NCBI GENE ID NUMBER: 7251
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
- The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.
- FOR RESEARCH USE ONLY
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CATALOG NUMBER: 16-799
- Size: 50 uL
- List Price: $295.00
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