Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse, Primate
- IMMUNOGEN: A recombinant protein fragment within the C-terminal region of TRBP2 was used as the immunogen for this antibody.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: Western blot: 5-10 ug/ml
Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.
Properties
- PURIFICATION: Protein A Affinity Chromatography
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
- CONCENTRATION: 0.5 mg/mL
- STORAGE CONDITIONS: Aliquot and Store at -20°C. Avoid freez-thaw cycles.
Additional Info
- NCBI OFFICIAL SYMBOL: TARBP2
- ADDITIONAL NAMES: RISC-loading complex subunit TARBP2 {ECO:0000255 | HAMAP-Rule:MF_03034}, TAR RNA-binding protein 2, Trans-activation-responsive RNA-binding protein, TARBP2 {ECO:0000255 | HAMAP-Rule:MF_03034}, TRBP
- NCBI GENE ID NUMBER: 6895
- USER NOTE: Optimal dilutions for each application to be determined by the researcher
Background
- TRBP2 (TAR (HIV-1) RNA binding protein 2) , along with Dicer and Argonaute-2, is part of the RISC (RNA induced silencing complex). As part of the RISC, TRBP2 is important in viral defense. Dicer cleaves dsRNA into siRNA. Through TRBP2-Dicer interaction, the siRNA template is loaded onto Argonaute-2, which cleaves encountered viral mRNA strands complementary to the loaded siRNA base-pair sequence.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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