TP53BP2 Antibody
CATALOG NUMBER: 58-427- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This TP53BP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-122 amino acids from the N-terminal region of human TP53BP2.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 126 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: TP53BP2
- ADDITIONAL NAMES: Apoptosis-stimulating of p53 protein 2, Bcl2-binding protein, Bbp, Renal carcinoma antigen NY-REN-51, Tumor suppressor p53-binding protein 2, 53BP2, p53-binding protein 2, p53BP2, TP53BP2, ASPP2, BBP
- Protein Accession Number: Q13625
- PROTEIN GI NUMBER: 33860140
- NCBI GENE ID NUMBER: 7159
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- TP53BP2 is a member of the ASPP(apoptosis-stimulating protein of p53) family of p53 interactingproteins. The protein contains four ankyrin repeats and an SH3domain involved in protein-protein interactions. It is localized tothe perinuclear region of the cytoplasm, and regulates apoptosisand cell growth through interactions with other regulatorymolecules including members of the p53 family. Multiple transcriptvariants encoding different isoforms have been found for this gene.
- 1: Rose, J. Phd, et al. Mol. Med. (2010) In press :
- 2: Zhao, J., et al. Hepatology 51(1):142-153(2010)
- 3: Hirata, H., et al. J. Urol. 182(2):721-727(2009)
- 4: Kweekel, D.M., et al. Br. J. Cancer 101(2):357-362(2009)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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