TNNI3 Antibody
CATALOG NUMBER: 59-004- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human, Mouse
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse
- IMMUNOGEN: This TNNI3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-114 amino acids from the Central region of human TNNI3.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 24 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: TNNI3
- ADDITIONAL NAMES: Troponin I, cardiac muscle, Cardiac troponin I, TNNI3, TNNC1
- Protein Accession Number: P19429
- PROTEIN GI NUMBER: 136213
- NCBI GENE ID NUMBER: 7137
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Troponin I (TnI), along with troponin T (TnT) and troponinC (TnC), is one of 3 subunits that form the troponin complex of thethin filaments of striated muscle. TnI is the inhibitory subunit;blocking actin-myosin interactions and thereby mediating striatedmuscle relaxation. The TnI subfamily contains three genes:TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, andTnI-cardiac. This gene encodes the TnI-cardiac protein and isexclusively expressed in cardiac muscle tissues. Mutations in thisgene cause familial hypertrophic cardiomyopathy type 7 (CMH7) andfamilial restrictive cardiomyopathy (RCM).
- 1: Millat, G., et al. Clin. Chim. Acta 411 (23-24), 1983-1991 (2010) :
- 2: Murakami, C., et al. Leg Med (Tokyo) 12(6):280-283(2010)
- 3: Millat, G., et al. EurMed Genet 53(5):261-267(2010)
- 4: Di Chiara, A., et al.Cardiovasc Med (Hagerstown) 11(8):587-592(2010)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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