Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This TNIP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 165-194 amino acids from the Central region of human TNIP2.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 49 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: TNIP2
- ADDITIONAL NAMES: TNFAIP3-interacting protein 2, A20-binding inhibitor of NF-kappa-B activation 2, ABIN-2, Fetal liver LKB1-interacting protein, TNIP2 {ECO:0000312 | EMBL:EAW825141}
- Protein Accession Number: Q8NFZ5
- PROTEIN GI NUMBER: 74715616
- NCBI GENE ID NUMBER: 79155
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- TNIP2 binds to the C-terminal zinc finger domain of A20(TNFAIP3; MIM 191163) and is involved in activation of the ERK (seeMAPK3; MIM 601795) MAP kinase pathway in various cell types (VanHuffel et al., 2001 [PubMed 11390377]; Papoutsopoulou et al., 2006[PubMed 16633345]).
- 1: Raychaudhuri, S., et al. Nat. Genet. 41(12):1313-1318(2009)
- 2: Handoyo, H., et al. Biochem. J. 424(1):109-118(2009)
- 3: Verstrepen, L., et al. Biochem. Pharmacol. 78(2):105-114(2009)
- 4: Huang, L., et al. Oncogene 27(47):6131-6140(2008)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
$65 Standard Overnight flat rate for as many products shipped within the United States.
$35 Dry Ice Shipment fee may be required on some items.
Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.