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Home / ELISA / Thrombomodulin Antibody [THBD/1782]
Thrombomodulin Antibody [THBD/1782]Thrombomodulin Antibody [THBD/1782]Thrombomodulin Antibody [THBD/1782]
Thrombomodulin Antibody [THBD/1782]
Thrombomodulin Antibody [THBD/1782]
Thrombomodulin Antibody [THBD/1782]

Thrombomodulin Antibody [THBD/1782]

CATALOG NUMBER: 33-688
  • Clonality: Monoclonal
  • Tested Applications: ELISA, Flow, IF, IHC-P, WB
  • Host Species: Mouse
  • Species Reactivity: Human
  • Conjugate: Unconjugated
  • Size: 100 ug

Specifications

  • HOST SPECIES: Mouse
  • SPECIES REACTIVITY: Human
  • IMMUNOGEN: Human recombinant partial protein corresponding to amino acids 69-194 was used as the immunogen for this Thrombomodulin antibody.
  • CONJUGATE: Unconjugated
  • TESTED APPLICATIONS: ELISA, Flow, IF, IHC-P, WB
  • APPLICATION NOTE: Flow Cytometry: 0.5-1ug/10^6 cells in 0.1ml
    IF: 0.5-1 ug/ml
    IHC (FFPE): 1-2 ug/ml for 30 min at RT
    ELISA: 2-4 ug/ml; order the BSA-free formulation for coating
    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the Thrombomodulin antibody to be titered up or down for optimal performance.

Properties

  • PURIFICATION: Protein G affinity chromatography
  • CLONALITY: Monoclonal
  • ISOTYPE: IgG2a, kappa
  • PHYSICAL STATE: Liquid
  • BUFFER: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
  • CONCENTRATION: 0.2 mg/mL
  • STORAGE CONDITIONS: Aliquot and Store at 2-8°C. Avoid freez-thaw cycles.

Additional Info

  • NCBI OFFICIAL SYMBOL: THBD
  • NCBI GENE ID NUMBER: 7056
  • USER NOTE: Optimal dilutions for each application to be determined by the researcher

Background

  • It recognizes a protein of 75kDa, identified as Thrombomodulin. Thrombomodulin is a transmembrane glycoprotein with natural anticoagulant properties. It is normally expressed by a restricted number of cells, such as endothelial and mesothelial cells. In addition, synovial lining and syncytio-trophoblasts of placenta also express thrombomodulin. This protein is present in almost all of benign vascular tumors and majority of malignant vascular tumors (Kaposi s sarcoma, angiosarcoma, and epithelioid hemangioendothelioma). Hence, anti-thrombomodulin serves as a sensitive marker for lymphatic endothelial cells and their tumors. Recently, thrombomodulin antibody has been used for mesothelial cells and malignant mesotheliomas.

Disclaimer

  • FOR RESEARCH USE ONLY
    For additional information, visit ProSci's Terms & Conditions Page.
  • Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER: 33-688

  • Size: 100 ug
  • List Price: $555.00
Datasheet
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