TGFBI Antibody
CATALOG NUMBER: 58-664- Clonality: Polyclonal
- Tested Applications: Flow, WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- HOMOLOGY: Predicted species reactivity based on immunogen sequence: Mouse, Pig, Rabbit
- IMMUNOGEN: This TGFBI antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-135 amino acids from the N-terminal region of human TGFBI.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: Flow, WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50 - PREDICTED MOLECULAR WEIGHT: 75 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: TGFBI
- ADDITIONAL NAMES: Transforming growth factor-beta-induced protein ig-h3, Beta ig-h3, Kerato-epithelin, RGD-containing collagen-associated protein, RGD-CAP, TGFBI, BIGH3
- Protein Accession Number: Q15582
- PROTEIN GI NUMBER: 2498193
- NCBI GENE ID NUMBER: 7045
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene encodes an RGD-containing protein that binds totype I, II and IV collagens. The RGD motif is found in manyextracellular matrix proteins modulating cell adhesion and servesas a ligand recognition sequence for several integrins. Thisprotein plays a role in cell-collagen interactions and may beinvolved in endochondrial bone formation in cartilage. The proteinis induced by transforming growth factor-beta and acts to inhibitcell adhesion. Mutations in this gene are associated with multipletypes of corneal dystrophy.
- 1: Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- 2: Edelstein, S.L., et al. Cornea 29(6):698-700(2010)
- 3: Romero, P., et al. Mol. Vis. 16, 1601-1609 (2010) :
- 4: Paliwal, P., et al. Mol. Vis. 16, 1429-1438 (2010) :
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
$65 Standard Overnight flat rate for as many products shipped within the United States.
$35 Dry Ice Shipment fee may be required on some items.
Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.
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