TEC Antibody
CATALOG NUMBER: 58-456- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This TEC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human TEC.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 74 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: TEC
- ADDITIONAL NAMES: Tyrosine-protein kinase Tec, TEC, PSCTK4
- Protein Accession Number: P42680
- PROTEIN GI NUMBER: 158518392
- NCBI GENE ID NUMBER: 7006
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- TEC belongs to the Tec familyof non-receptor protein-tyrosine kinases containing a pleckstrinhomology domain. Tec family kinases are involved in theintracellular signaling mechanisms of cytokine receptors,lymphocyte surface antigens, heterotrimeric G-protein coupledreceptors, and integrin molecules. They are also key players in theregulation of the immune functions. Tec kinase is an integralcomponent of T cell signaling and has a distinct role in T cellactivation. This gene may be associated with myelodysplasticsyndrome.
- 1: Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- 2: Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- 3: Ebert, A.D., et al. Traffic 11(6):813-826(2010)
- 4: Susaki, K., et al. Immunol. Lett. 127(2):135-142(2010)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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