Specifications
- HOST SPECIES: Hamster
- SPECIES REACTIVITY: Mouse
- IMMUNOGEN: Mouse T cell clone G8
- CONJUGATE: PE
- TESTED APPLICATIONS: Flow
- APPLICATION NOTE: TCR gamma delta Antibody [UC7-13D5] for use in flow cytometry assays.
- SPECIFICITY: TCRgammadelta
Properties
- CLONALITY: Monoclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS/NaN3 and a stabilizing agent
- CONCENTRATION: 0.1 mg/mL
- STORAGE CONDITIONS: Store vial at 2-8°C
Additional Info
- NCBI OFFICIAL SYMBOL: Tcrd
- NCBI GENE ID NUMBER: 110066;110067
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- The TCRgammadelta heterodimer of the CD3/T cell receptor complex is clonotypic and consists of Ig-like variable and constant domains. It is expressed during thymopoiesis and on the small subpopulation of gammadelta TCR-expressing T lymphocytes in the periphery. The majority of T cells present in some epithelial tissues are gammadelta+ and have limited receptor diversity. The TCRgammadelta heterodimer recognizes peptide antigen bound to MHC antigens and subsequent signal transduction mediated by the invariant chains leads to T cell activation. The monoclonal antibody UC7-13D5 is specific for the gammadelta heterodimer and plate-bound UC7-13D5 activates gammadelta TCR-bearing cells. This antibody does not react with alphabeta TCR-expressing T cells.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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