Specifications
- HOST SPECIES: Chicken
- SPECIES REACTIVITY: Human
- IMMUNOGEN: 1-114
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: T-cell leukemia/lymphoma protein 1A antibody can be used for the detection of T-cell leukemia/lymphoma protein 1A by Western Blot.
- PREDICTED MOLECULAR WEIGHT: 13.5 kDa (calculated)
Properties
- PURIFICATION: Immunoaffinity Purified
- CLONALITY: Polyclonal
- PHYSICAL STATE: Liquid
- BUFFER: Phosphate-Buffered Saline. No preservatives added.
- CONCENTRATION: 1 mg/mL
- STORAGE CONDITIONS: TCL1A antibody can be stored at 4°C for short term (weeks). Long term storage should be at -20°C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: TCL1A
- ADDITIONAL NAMES: TCL1Oncogene TCL-1, Oncogene TCL1, Tcell leukemia/lymphoma protein 1A, P14 TCL1 protein, TCL1 oncogene, TCL-1 protein
- Protein Accession Number: NP_068801.1
- PROTEIN GI NUMBER: 11415028
- NCBI GENE ID NUMBER: 8115
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- DISEASE: Chromosomal aberrations activating TCL1A are found in chronic T-cell leukemias (T-CLL). Translocation t(14;14)(q11;q32); translocation t(7;14)(q35;q32); inversion inv(14)(q11;q32) that involves the T-cell receptor α/Δ locuses.
SUBUNIT: Homodimer.
SIMILARITY: Belongs to the TCL1 family.
SUBCELLULAR LOCATION: Microsomal fraction.
TISSUE SPECIFICITY: Restricted in the T-cell lineage to immature thymocytes and activated peripheral lymphocytes. Preferentially expressed early in T- and B-lymphocyte differentiation.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
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