TBX3 Antibody
CATALOG NUMBER: 58-144- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This TBX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 310-338 amino acids from the Central region of human TBX3.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 79 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: TBX3
- ADDITIONAL NAMES: T-box transcription factor TBX3, T-box protein 3, TBX3
- Protein Accession Number: O15119
- NCBI GENE ID NUMBER: 6926
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene is a member of a phylogenetically conservedfamily of genes that share a common DNA-binding domain, the T-box.T-box genes encode transcription factors involved in the regulationof developmental processes. This protein is a transcriptionalrepressor and is thought to play a role in the anterior/posterioraxis of the tetrapod forelimb. Mutations in this gene causeulnar-mammary syndrome, affecting limb, apocrine gland, tooth,hair, and genital development. Alternative splicing of this generesults in three transcript variants encoding different isoforms;however, the full length nature of one variant has not beendetermined.
- 1: Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- 2: Hong, K.W., et al. J. Hum. Genet. 55(6):336-341(2010)
- 3: Christoffels, V.M., et al. Circ. Res. 106(2):240-254(2010)
- 4: Pfeufer, A., et al. Nat. Genet. 42(2):153-159(2010)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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