Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human TARDBP (NP_031401.1).
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IF, IHC, IP, RIP, WB
- APPLICATION NOTE: WB: 1:500 - 1:2000
IHC: 1:50 - 1:100
IF: 1:20 - 1:100
IP: 1:50 - 1:100
RIP: 1:20 - 1:50 - POSITIVE CONTROL 1: HeLa
- POSITIVE CONTROL 2: Jurkat
- POSITIVE CONTROL 3: SW620
- POSITIVE CONTROL 4: HT-29
- POSITIVE CONTROL 5: A-673
- POSITIVE CONTROL 6: Es-2
- PREDICTED MOLECULAR WEIGHT: Observed: 42kDa
Properties
- PURIFICATION: Affinity purification
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at -20°C. Avoid freeze / thaw cycles.
Additional Info
- NCBI OFFICIAL SYMBOL: TARDBP
- ADDITIONAL NAMES: TDP43 Antibody: ALS10, TDP-43, TDP43, TAR DNA-binding protein 43
- NCBI GENE ID NUMBER: 23435
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
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