Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- HOMOLOGY: Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat, Xenopus
- IMMUNOGEN: This TARBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-89 amino acids from the N-terminal region of human TARBP2.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IHC-P, WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50 - PREDICTED MOLECULAR WEIGHT: 39 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: TARBP2
- ADDITIONAL NAMES: RISC-loading complex subunit TARBP2 {ECO:0000255 | HAMAP-Rule:MF_03034}, TAR RNA-binding protein 2, Trans-activation-responsive RNA-binding protein, TARBP2 {ECO:0000255 | HAMAP-Rule:MF_03034}, TRBP
- Protein Accession Number: Q15633
- PROTEIN GI NUMBER: 209572714
- NCBI GENE ID NUMBER: 6895
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- HIV-1, the causative agent of acquired immunodeficiencysyndrome (AIDS), contains an RNA genome that produces achromosomally integrated DNA during the replicative cycle.Activation of HIV-1 gene expression by the transactivator Tat isdependent on an RNA regulatory element (TAR) located downstream ofthe transcription initiation site. The protein encoded by this genebinds between the bulge and the loop of the HIV-1 TAR RNAregulatory element and activates HIV-1 gene expression in synergywith the viral Tat protein. Alternative splicing results inmultiple transcript variants encoding different isoforms. This genealso has a pseudogene.
- 1: Garre, P., et al. Nat. Genet. 42(10):817-818(2010)
- 2: Wilker, E.H., et al. Environ. Health Perspect. 118(7):943-948(2010)
- 3: Boni, V., et al. Pharmacogenomics J. (2010) In press :
- 4: Wang, H.W., et al. Nat. Struct. Mol. Biol. 16(11):1148-1153(2009)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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