Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This TAC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-83 amino acids from the Central region of human TAC3.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IHC-P, WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50 - PREDICTED MOLECULAR WEIGHT: 13 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: TAC3
- ADDITIONAL NAMES: Tachykinin-3, ZNEUROK1, Neurokinin-B, NKB, Neuromedin-K, TAC3, NKNB
- Protein Accession Number: Q9UHF0
- PROTEIN GI NUMBER: 18203501
- NCBI GENE ID NUMBER: 6866
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene encodes a member of the tachykinin family ofsecreted neuropeptides. The encoded protein is primarily expressedin the central and peripheral nervous system and functions as aneurotransmitter. This protein is the ligand for the neurokinin-3receptor. This protein is also expressed in the outersyncytiotrophoblast of the placenta and may be associated withpregnancy-induced hypertension and pre-eclampsia. Mutations in thisgene are associated with normosmic hypogonadotropic hypogonadism.Alternate splicing results in multiple transcript variants.
- 1: Klassert, T.E., et al. J. Neuroimmunol. 227 (1-2), 202-207 (2010) :
- 2: Hrabovszky, E., et al. Eur. J. Neurosci. 31(11):1984-1998(2010)
- 3: Gianetti, E., et al. J. Clin. Endocrinol. Metab. 95(6):2857-2867(2010)
- 4: Young, J., et al. J. Clin. Endocrinol. Metab. 95(5):2287-2295(2010)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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