SYT1 Antibody
CATALOG NUMBER: 57-214- Clonality: Polyclonal
- Tested Applications: IHC-P, WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- HOMOLOGY: Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Monkey, Mouse, Rat
- IMMUNOGEN: This SYT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 349-377 amino acids from the C-terminal region of human SYT1.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IHC-P, WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50 - PREDICTED MOLECULAR WEIGHT: 48 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: SYT1
- ADDITIONAL NAMES: Synaptotagmin-1, Synaptotagmin I, SytI, p65, SYT1, SVP65, SYT
- Protein Accession Number: P21579
- PROTEIN GI NUMBER: 135086
- NCBI GENE ID NUMBER: 6857
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- The synaptotagmins are integral membrane proteins ofsynaptic vesicles thought to serve as Ca(2+) sensors in the processof vesicular trafficking and exocytosis. Calcium binding tosynaptotagmin-1 participates in triggering neurotransmitter releaseat the synapse (Fernandez-Chacon et al., 2001 [PubMed11242035]).
- 1: Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- 2: Musch, M.W., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 298 (2), G203-G211 (2010) :
- 3: Kathir, K.M., et al. Biochim. Biophys. Acta 1798(2):297-302(2010)
- 4: Pattaro, C., et al. BMC Med. Genet. 11, 41 (2010) :
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
$65 Standard Overnight flat rate for as many products shipped within the United States.
$35 Dry Ice Shipment fee may be required on some items.
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