Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse
- IMMUNOGEN: A recombinant protein fragment from the N-terminal region of human Syndecan 4 was used as the immunogen for this antibody.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: Western blot: 2-5 ug/ml
Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.
Properties
- PURIFICATION: Protein A affinity chromatography
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
- CONCENTRATION: 0.5 mg/mL
- STORAGE CONDITIONS: Aliquot and Store at -20°C. Avoid freez-thaw cycles.
Additional Info
- NCBI OFFICIAL SYMBOL: SDC4
- ADDITIONAL NAMES: Syndecan-4, SYND4, Amphiglycan, Ryudocan core protein, SDC4
- NCBI GENE ID NUMBER: 6385
- USER NOTE: Optimal dilutions for each application to be determined by the researcher
Background
- Syndecans are a family of four transmembrane proteoglycans divided into two subfamilies based on transmembrane and cytoplasmic domain similarity: Syndecan 1/3 and 2/4. Via their covalently attached heparan sulphate chains, they bind a variety of ligands and play a role in a number of cell functions including adhesion, proliferation and migration. Syndecan 4 is highly expressed on the cell surface of epithelial cells and fibroblasts and plays an important role in tissue repair. Integrin-mediated binding of fibronectin to Syndecan-4 induces focal adhesions and formation of cytoskeletal stress fibers, facilitating wound healing.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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