Synaptophysin Antibody
CATALOG NUMBER: 50-192- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Mouse, Rat
- Conjugate: Unconjugated
- Size: 0.1 mL
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Mouse, Rat
- IMMUNOGEN: Peptide corresponding to amino acid residues from the C-terminal region of rat synaptophysin 2, conjugated to keyhole limpet hemocyanin (KLH).
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- PREDICTED MOLECULAR WEIGHT: 38
Properties
- PURIFICATION: Affinity Purified
- CLONALITY: Polyclonal
- PHYSICAL STATE: Liquid
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Synaptophysin antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
Additional Info
- NCBI OFFICIAL SYMBOL: Synpr
- Protein Accession Number: P22831
- PROTEIN GI NUMBER: 33112632
- NCBI GENE ID NUMBER: 66030
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Synaptophysin 2, also known as synaptoporin, is a component of the synaptic vesicle membrane and thought to play an important role in synaptic vesicle trafficking (Dai et al., 2003). It is highly homologous to synaptophysin 1, yet differs in expression. Whereas synaptophysin 1 is ubiquitiously expressed, synaptophysin 2 is concentrated in the mossy fiber synapses of the hippocampus (Grabs et al., 1994; Singec et al., 2002).
- 1: Dai J, Ji C, Gu S, Wu Q, Wang L, Xu J, Zeng L, Ye X, Yin G, Xie Y, Mao Y (2003) Cloning and sequence analysis of the human cDNA encoding the synaptoporin, a highly conserved synaptic vesicle protein. Molecular Biology Reports 30:185-191.
- 2: Singec I, Knoth R, Ditter M, Hagemeyer CE, Rosenbrock H, Frotscher M, Volk B (2002) Synaptic vesicle protein synaptoporin is differently expressed by subpopulations of mouse hippocampal neurons. J Comp Neurol 452(2):139-153.
- 3: Grabs D, Bergmann M, Schuster T, Fox PA, Brich M, Gratz M (1994) Differential expression of synaptophysin and synaptoporin during pre- and postnatal development of the rat hippocampal network. Eur J Neurosci. 6(11): 1765-71..
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: This product is for research use only.
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